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Dissolution testing (EP 2.9.3)

In dissolution testing the release of API (active pharmaceutical ingredient) from tablets/capsules is tested. Often dissolution testing is an important parameter in the development of new medical products - DB Lab are very experienced in performing these tests and may be a valuable business partner when the dissolution profile of new formulations is tested. Dissolution is often part of the release testing and is also a central part of the tests during stability studies.

FACTS

DB Lab has dissolution equipment with basket (Apparatus) og paddle (Apparatus 2). We perform dissolution testing on various types of dosage units:

”Conventional-release solid dosage forms” - tablets or capsules which are dissolved within one hour

”Prolonged-release solid dosage forms”, tablets or capsules which are dissolved over a longer period of time, e.g. within 8 or 24 hours

”Delayed-release solid dosage forms”, with change of media during the test. This test is usually performed with entero-coated tablets